bullet Sensors & Transducers Journal

    (ISSN 1726- 5479)

205.767

2008 e-Impact Factor

25 Top Downloaded Articles

Best Selling Articles 2012

Journal Subscription 2013

Editorial Calendar 2013

Submit an Article

Editorial Board

Current Issue

S&T journal's cover

Sensors & Transducers Journal 2011

Sensors & Transducers Journal 2010

Sensors & Transducers Journal 2009

Sensors & Transducers Journal 2008

Sensors & Transducers Journal 2007

2000-2002 S&T e-Digest Contents

2003 S&T e-Digest Contents

2004 S&T e-Digest Contents

2005 S&T e-Digest Contents

2006 S&T e-Digest Contents

 

Best Articles 2011

 

 

 

Vol. 156, Issue 9, September 2013, pp. 368-373

 

Bullet

 

Aptamer Biosensor for Antibiotic Residues Detection in Food Analysis
 
1, 2 Yemin Guo, * 2 Xiangyou Wang, * 2 Xia Sun

1 School of Engineering, Northeast Agricultural University, No. 59 Mucai Street Xiangfang Distrct Harbin, P. R. China

2 School of Agriculture and Food Engineering, Shandong University of Technology, No. 12, Zhangzhou Road, Zibo 255049, Shandong Province, P. R. China

* Tel.:+86-533-2786558, fax: +86-533-2786558
E-mail: wxy@sdut.edu.cn

 

Received: 23 August 2013   /Accepted: 25 August 2013   /Published: 30 September 2013

Digital Sensors and Sensor Sysstems

 

Abstract: Antibiotics are widely used to kill or inhibit microorganisms, but their abuse results in various types of side effects in humans and the appearance of super bacteria with tolerance to antibiotics. Excess residual antibiotics in food products have become a serious problem, and so a more reliable, accurate, and easier detection system has been required. Aptamers have strong potential as sensitive bioprobes for the development of biosensors for antibiotics detection, a specially designed aptamer for an antibiotic may be suitable for this purpose. Aptamers are synthetic RNA or DNA single-stranded oligonu-cleotide sequences which can be generated by an in vitro selection process called SELEX (Systematic Evolution of Ligands by Exponential enrichment) technique. Antibiotics are small molecule targets, therefore, they cannot act as an antigen independently and high specificity and affinity antibiotics antibody are difficult to prepare. Aptamers have advantages over antibodies, such as easy chemical synthesis, easy modification, and less immunogenic response, thus, which can be considered as a valid alternative to antibodies receptors to bind to the target molecules with high affinity. In this review, we concentrated on recent advances made in detection and quantification of antibiotics residues with aptamers biosensor. In this paper, the preparation of aptamers biosensor, the selection of analysis methods and the detection of real samples are introduced in detail. Future prospects toward the development of selective, sensitive aptamers biosensor systems are also discussed.

 

Keywords: Antibiotics residues, Detection, Aptamers, Biosensor.

 

Acrobat reader logo Click <here> or title of paper to download the full pages article in pdf format

 

 

Download <here> the Library Journal Recommendation Form

 

 

Read more about Biosensors

 

 

 

 

 

 


1999 - 2018 Copyright , International Frequency Sensor Association (IFSA). All Rights Reserved.


Home - News - Links - Archives - Tools - Voltage-to-Frequency Converters - Standardization - Patents - Marketplace - Projects - Wish List - e-Shop - Sensor Jobs - Membership - Videos - Publishing - Site Map - Subscribe - Search

 Members Area -Sensors Portal -Training Courses - S&T Digest - For advertisers - Bookstore - Forums - Polls - Submit Press Release - Submit White Paper - Testimonies - Twitter - Facebook - LinkedIn