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Vol. 161, Issue 12, December 2013, pp. 437-451




A Review of Recent Developments in Acetylcholinesterase Biosensors
Yemin Guo, Zhili Gong, Xia Sun *, Xiangyou Wang *

School of Agriculture and Food Engineering, Shandong University of Technology, No. 12, Zhangzhou Road, Zibo 255049, Shandong Province, P. R. China
Tel.:+86-533-2786558, fax: +86-533-2786558
E-mail: sunxia2151@sina.com, wxy@sdut.edu.cn


Received: 1 October 2013   /Accepted: 22 November 2013   /Published: 30 December 2013

Digital Sensors and Sensor Sysstems


Abstract: Over the past decades, acetylcholinesterase (AChE) biosensors have emerged as a highly simple, rapid, and ultra-sensitive technique for pesticide analysis in environmental monitoring, food safety, and quality control. In this paper, we will highlight the research efforts over the last ten years in fabricating AChE biosensors, the recent trends and future prospects for the development of better AChE biosensing systems. Research on various immobilization methods, different strategies for biosensor construction, the performance and application of constructed AChE biosensors are extensively introduced in this review.


Keywords: Acetylcholinesterase biosensors, Inhibition, Electrochemical, Pesticide residues, Immobilization.


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