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Vol. 162, Issue 1, January 2014, pp. 42-46

 

Bullet

 

Studies of the Synchronous Sensing Method in the Microfluidic Cell Impedance Detection
 

1 Jie DAI, 2 Yuhwa LO, 1 Kecheng YANG

1 School of Optical and Electronic information, Huazhong University of Science and Technology, Wuhan 430074, China
2 Department of Electrical and Computer Engineering, University of California at San Diego, La Jolla, CA, 92093-0407, United States of America

E-mail: kcyang@mail.hust.edu.cn

 

Received: 21 October 2013 /Accepted: 9 January 2014 /Published: 31 January 2014

Digital Sensors and Sensor Sysstems

 

Abstract: Microfluidic impedance sensors play a significant role in point-of-care applications, clinical tests and laboratory studies. Instead of the traditional signal process method with the envelope detector, filter banks and multistage amplifier, we have reported a new implement using synchronous sampling and orthogonal detecting. By studying the intensity and phase modulation in the cell impedance sensing progress, we have calculated the SNR of the new method compare with the raw data. Base on the physical model and the calculation, we have demonstrated a simulation result which shows a capability to detect the signal of 1um cell in a noisy environment.

 

Keywords: Phase, Orthogonal wave, Multiply-add operation, Noise inhibition, Synchronous sampling.

 

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