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Vol. 183, Issue 12, December 2014, pp. 34-41

 

Bullet

 

Comparison of Biocomposite Electrode Sensor for the Detection of Oxidative Reactions
 

1 Solomon W. LEUNG, 2 David ASSAN, 3 James C. K. LAI

1 Civil & Environmental Engineering Department and Biomedical Research Institute, Idaho State University, Pocatello, ID 83209, USA
2 Civil & Environmental Engineering Department, School of Engineering, Box 8060, Idaho State University, Pocatello, ID 83209, USA
3 Biomedical and Pharmaceutical Sciences Department and Biomedical Research Institute, Idaho State University, Pocatello, ID 83209, USA
Tel.: 1, 2 208-282-2524, 3 208-282-2275, 1 fax: 208-282-4538, 2, 3 208-282-4305

E-mail: leunsolo@isu.edu, assadavi@isu.edu, lai@pharmacy.isu.edu

 

Received: 21 October 2014 /Accepted: 28 November 2014 /Published: 31 December 2014

Digital Sensors and Sensor Sysstems

 

Abstract: Hemoglobin has a very strong affinity with oxygen and thus is a good catalyst to carry oxygen for many oxidation reactions. Many researchers have explored this property of hemoglobin to develop sensors for the detection of nitrite and peroxide that are important in biomedical and environmental monitoring. We have previously reported the development of biosensors that can detect nitrite and peroxide with a lower detecting limit below 1´1012 M, that were among the best detectors at the time. With a similar sensor platform, we have now developed a biosensor that can detect the oxidation reaction orders of magnitude better than the previous sensors. The sensor comprises layers of biocomposite made up of a polymer, nanogold particles, and a complex protein on the surface of an electrode. The performance of this electrode biosensor is compared with the previously developed sensors, the durability and other factors that can affect the performance and fabrication of this biosensor are discussed.

 

Keywords: Oxidation, Nitrite, Peroxide, Nanogold particles, Biosensor.

 

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