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Vol. 189, Issue 6, June 2015, pp. 137-142

 

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A Portable Micro-electrochemical System for Rapid Detection of Cancer Cells
 

Xiao Chen, Qiwei Li, Wei Liu, Changyu Wu, * Xuemei Wang

State Key Laboratory of Bioelectronics (Chien-Shiung Wu Laboratory), Southeast University, No. 2 Sipailou, Nanjing 210096, People’s Republic of China
Tel.: +86 02583792177, fax: +86 02583792177

* E-mail: xuewang@seu.edu.cn

 

Received: 24 April 2015 /Accepted: 29 May 2015 /Published: 30 June 2015

Digital Sensors and Sensor Sysstems

 

Abstract: High sensitive and rapid detection of cancer cells is important to diagnosis and treatment of cancer. This study presented a portable micro-electrochemical system for detection of cancer cells by measuring electrochemical behaviors of molecule probe. The relevant hardware was divided into three parts, i.e., MCU circuit module, current measuring circuit module and potentiostatic circuit module. Information between modules exchanged through the system bus. The software was designed for generating and acquisition of signals, communication between master and slave, and data analysis. The performance of this portable micro-electrochemical system was validated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) of potassium hexacyanoferrate (III) solution at ITO electrode. Based on this portable instrumental system, a rapid detection of cancer cells was realized by using electrochemical probes. This puts forward to the portable micro-electrochemical system for rapid detection and diagnosis of cancers in clinical application.

 

Keywords: Portable micro-electrochemical system, Cancer cell detection, Hardware and software design, ITO electrode.

 

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