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Vol. 98, Issue 11, November 2008, pp.16-25





Glucose Biosensor Based on Electrostatically Functionalized Carbon Nanotubes Bound Glucose Oxidase

Suman, bAshok Kumar, aV. K. Jain

aInstitute of Advance Research and Studies (Material and Devices), Amity University,

Sector- 125, Noida, India, 201303

bInstitute of Genomics and Integrative Biology, Mall Road, Delhi, India, 110007

*Tel.: +91-120-4392507

*E-mail: snagpal@amity.edu



Received: 19 August 2008   /Accepted: 17 November 2008   /Published: 30 November 2008


Abstract: A glucose biosensor has been fabricated by immobilizing glucose oxidase (GOD) onto electrostatically functionalized multiwalled carbon nanotubes (f-MWCNTs) modified glass plate electrode. The MWCNTs were functionalized by non chemical and dry process using corona discharge tube method. The resulting biosensor was characterized electrochemically and detection performances were evaluated. The optimum detection conditions and the stability of sensor were also studied. The results showed that the GOD/f-MWCNTs/GP glucose biosensor has lower detection sensitivity of 0.10 μA/mM and linearity up to 5 mM at lower working potential of 0.4 V. It has more than 85% of its initial activity after continuously using for three months. During this period the sensor was reused for about 150 times. The sensor was also unaffected by the various serum interfering agents. The present GOD/f-MWCNTs/ GP glucose biosensor showed excellent sensitivity, reproducibility and remarkable stability.


Keywords: Glucose biosensor; Electrostatically functionalized MWCNTs, CNT Glucose sensor


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