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Vol. 125, Issue 2, February 2011, pp.30-41

 

Bullet

Glucose Monitoring System Based on Osmotic Pressure Measurements

 

1Alexandra LEAL, 1,2António VALENTE, 1Ana FERREIRA, 1,2Salviano SOARES, 3Vitor RIBEIRO, 4Olga KRUSHINITSKAYA, and 4Erik A. JOHANNESSEN

1UTAD - University, Quinta de Prados, 5001-911 Vila Real, Portugal

2IEETA, Aveiro, Portugal

3PT-Inovação, Aveiro, Portugal

4Vestfold University College, Tønsberg, Norway

Tel.: +351259350372, +351259350480

E-mail: avalente@utad.pt

 

 

Received: 27 October 2011   /Accepted: 15 February 2011   /Published: 28 February 2011

 

Abstract: This paper presents the design and development of a prototype sensor unit for implementation in a long-term glucose monitoring system suitable for estimating glucose levels in people suffering from diabetes mellitus. The system utilizes osmotic pressure as the sensing mechanism and consists of a sensor prototype that is integrated together with a pre-amplifier and data acquisition unit for both data recording and processing. The sensor prototype is based on an embedded silicon absolute pressure transducer and a semipermeable nanoporous membrane that is enclosed in the sensor housing. The glucose monitoring system facilitates the integration of a low power microcontroller that is combined with a wireless inductive powered communication link. Experimental verification have proven that the system is capable of tracking osmotic pressure changes using albumin as a model compound, and thereby show a proof of concept for novel long term tracking of blood glucose from remote sensor nodes.

 

Keywords: Glucose sensor, Continuous, Semipermeable membrane, Osmosis, Osmotic pressure

 

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