Biosensors Could Detect Poisons or Proteins in Blood Samples. A fundamental science discovery made by UK, Belgian and US research groups has resulted in tiny new sensor structures that could be used in highly-sensitive biosensors. The novel nanosensors could be tailor-made to instantly detect the presence of particular molecules, for example poisons or proteins in patients' blood samples, with high sensitivity. The researchers were led by Imperial College London physicists funded by the Engineering and Physical Sciences Research Council. The team showed that by putting together two specific nanostructures made of gold or silver, they can make an early prototype device which, once optimised, should exhibit a highly sensitive ability to detect particular chemicals in the immediate surroundings ...

Articles, Papers and References

S. Hauck, C. Koblinger, S. Drost, H. Wolf, Biosensor System for the Determination of Ochratoxin A, In Proceedings of the 12th European Conference on Solid-State Transducers and the 9th UK Conference on Sensors and their Applications, Southampton, UK, 13-16 September 1998, EUROSENSOR XII, Ed. by N. M. White, Institute of Physics Publishing Bristol and Philadelphia, Sensors Series, volume 1, pp. 515-518.

U.Schramm, T. Rechenbach, P.Boeker, S. Winter, C.Roesky, R.Pollex, E.Weber, P.Schulze Lammers, J. Bargon, Ammonia Sensor Based on Carboxylic-Acid Functionalized Cryptophanes and Macrocycles, In Proceedings of the 12th European Conference on Solid-State Transducers and the 9th UK Conference on Sensors and their Applications, Southampton, UK, 13-16 September 1998, EUROSENSOR XII, Ed. by N. M. White, Institute of Physics Publishing Bristol and Philadelphia, Sensors Series, volume 1, pp. 533-536.

P.Boeker, G. Horner, T. Rechenbach, U.Schramm, P.Schulze Lammers, J. Bargon,  Ammonia Detector for Emissions of Agricultural Origin, In Proceedings of the 12th European Conference on Solid-State Transducers and the 9th UK Conference on Sensors and their Applications, Southampton, UK, 13-16 September 1998, EUROSENSOR XII, Ed. by N. M. White, Institute of Physics Publishing Bristol and Philadelphia, Sensors Series, volume 2, pp. 913-916.

Powner E.T., Yalcinkaya F., Intelligent Biosensor, Sensor Review, Vol.17, No.2, 1997, pp.107-116

Abstract: Discusses intelligent materials, intelligent material-based sensors, their transducing methods and different kinds of transducers used with smart material-based sensors. Assumes that the future of intelligent sensors will almost totally dependent on intelligent chemistry and intelligent instrumentation. Molecular recognition will widen the horizons of smart systems with the help of VLSI-based  design and fabrication. Discusses different sensor mechanisms, such as ENFETs, immunoFETs, ISFETs and chemFETs and takes a detailed look at potentiometric, amperometric and optical biosensors.

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Biosensors related books are available for purchase online

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[1]. Tim H. Richardson, Functional Organic and Polymeric Materials: Molecular Functionality--Macroscopic Reality, 2000

[2]. A. Cunningham, Introduction to Bioanalytical Sensors, 1998

[3]. Ursula E. Spichiger-Keller, Chemical Sensors and Biosensors for Medical and Biological Applications, 1998

[4]. D.Diamond, Principles of Chemical and Biological Sensors, 1998

[5]. R. F.Taylor, J.S.Schultz, Principles of Chemical and Biological Sensors, 1998

[6]. L.G.Blum, Bio- and Chemi-Luminescent Sensors, 1997

[7]. G. Harsanyi, Sensors in Biomedical Applications Fundamentals Technology & Applications, 2000

[8]. E. Gizeli, C. R. Lowe, Biomolecular Sensors, 2002

[9]. Brian R. Eggins, Chemical Sensors and Biosensors, 2002

[10].E. Katz (Editor), Bioelectronics : From Theory to Applications, 2005

[11].Kim R. Rogers, Ashok Mulchandani, Affinity Biosensors: Techniques and Protocols

[12].Ligler, Rowe Taitt, F.S. Ligler, C.A. Rowe Taitt, Optical Biosensors: Present and Future

[13].Grattarola M., Massobrio G., Bioelectronics Handbook: MOSFETs, Biosensors, and Neurons