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Title: Smart Sensors and MEMS

Author: Sergey Y. Yurish (Editor), Maria Teresa S.R. Gomes (Editor)

Publisher: Springer Verlag

Hardcover: 480 pages

Pubdate: January, 2005

ISBN: 1402029276

Price: $ 89.95 (paperback), $ 199.00 (hardcover)

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Chapter 14. Electronic Biosensors Based on Biomaterial-Nanoparticle Hybrid Systems

(Eugenii Katz)




Nanomaterials such as metal or semiconductor nanoparticles and nanorods exhibit similar dimensions to those of biomolecules, such as proteins (enzymes, antigens, antibodies) or DNA. The integration of the nanoparticles, exhibiting unique electronic, photonic and catalytic properties, with the biomaterials, revealing unique recognition features or catalytic properties, yields novel hybrid nanobiomaterials of synergetic properties and functions. The present review article describes recent advances in the use of biomolecule-nanoparticle (metallic or semiconductive) assemblies for bioanalytical applications. In these systems the unique electronic, photonic, optical and catalytic properties of the nanoparticles are used to transduce the specific biorecognition and biocatalytic functions of the biomaterial components.


Keywords: biosensors, biomaterials, nanomaterials, enzyme, antigent, antibodie, nanoparticle, nanorods, DNA


Eugenii Katz, Professor, Dr., Institute of Chemistry, The Hebrew University of Jerusalem, Givat Ram, Jerusalem 91904, Israel, E-mail: ekatz@vms.huji.ac.il

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