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Vol. 144, No. 9, September 2012, pp. 182-191




PSoC Based Blood Coagulation Instrument for the Analysis of PT & APTT


1 School of Electrical and Electronics Engineering

Shanmuga Arts, Science, Technology & Research Academy (SASTRA)

Deemed University, Thanjavur-613 402,Tamil Nadu, India

2 PG and Research Department of Physics, A.V.V.M Sri Pushpam College, Poondi, Thanjavur, Tamil Nadu, India

E-mail: neelkeer@hotmail.com, raghoo_einstien@yahoo.com, drkmsys@yahoo.com



Received: 22 July 2012   /Accepted: 21 September 2012   /Published: 28 September 2012

Digital Sensors and Sensor Sysstems


Abstract: Internal bleeding and internal clotting is the a major cause of death in patients with chronic Hepatitis, Carcinoma, Hemophilia, patients undergoing anticoagulant therapy and Diabetic patients where the natural Blood clotting mechanism that coagulates and clots the bleeding injury doesn’t work properly. Blood coagulation analyzer is the best tool in diagnosing these patients towards deciding the course of treatment. Though there are several clotting factors which are involved in blood clotting mechanism, Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) are the major diagnostic tools in deciding the course of therapy and dosage. In this paper the design and development of Coagulation Analyzer using PSoC (Programmable System-on-Chip) CY8C28433 is presented. The designed Analytic Instrument has shown comparatively better results of Prothrombin Time and Activated Partial Thromboplastin Time with standard Instruments. The error on comparison is less than 2 % as agreed by international standards. The designed instrument is useful in diagnosing of internal bleeding and clotting by interpreting the results AT comparatively lower cost.


Keywords: Haemophilia,Warfarin, PT, APTT



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